Search Results - Biotechnology/Pharmaceuticals

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Guanfacine as an Anti-Virulence Agent in Pseudomonas Aeruginosa

Guanfacine as an Anti-Virulence Agent in Pseudomonas aeruginosaDocket# 19-3565-1Current anti-infective therapies against bacterial pathogens fall in two broad categories: vaccines and antibiotics. While vaccines serve in disease prevention, antibiotics kill pathogens after infection. However, since antibiosis creates a selective pressure for resist...
Published: 7/15/2019   |   Inventor(s): Mohammad Seyedsayamdost, Bethany Okada, Anran Li
Keywords(s):  
Category(s): Biotechnology/Pharmaceuticals

Keratinimicins and Keratinicyclins- Novel families of antibacterial and antiviral agents

Keratinimicins and Keratinicyclins- Novel families of antibacterial and antiviral agentsDocket# 18-3381-1Researchers at Princeton University have developed a rapid genetics-free method for eliciting and detecting cryptic metabolites. Utilizing this approach, the inventors have activated production of diverse cryptic metabolites and characterized se...
Published: 7/15/2019   |   Inventor(s): Mohammad Seyedsayamdost, Fei Xu, Yihan Wu, Leah Bushin, Katherine Davis
Keywords(s):  
Category(s): Biotechnology/Pharmaceuticals

Recombinant Phages for Targeted Bacterial Killing, Infection, Biodetection, and as a Means of Protein Extraction

Recombinant Phages for Targeted Bacterial Killing, Infection, Biodetection, and as a Means of Protein ExtractionPrinceton Docket # 19-3527Researchers in Princeton University’s Department of Molecular Biology have developed a recombinant phage platform technology that can be easily and precisely engineered for particular disease applications. ...
Published: 6/12/2019   |   Inventor(s): Justin Silpe, Bonnie Bassler
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Category(s): Biotechnology/Pharmaceuticals

X-Ray Assisted Electron Microscopy Staining Procedure

X-Ray Assisted Electron Microscopy Staining ProcedurePrinceton Docket # 19-3530Researchers in the Princeton Neuroscience Institute, Princeton University have developed an X-ray assisted staining procedure, which allows for tight control over the staining process and can serve as a very important and unique entry point for staining quality control w...
Published: 5/29/2019   |   Inventor(s): Adrian Wanner, David Tank, Sebastian Seung
Keywords(s):  
Category(s): Biotechnology/Pharmaceuticals

Method to Characterize Bacteria in Three-Dimensional Porous Media

Princeton Docket #19-3572Researchers at Princeton University have developed a novel method to characterize bacteria motion, self-organization, structure, and biological behavior in three-dimensional (3D) porous media by injecting them into a jammed hydrogel matrix. The matrix is self-healing and supports the weight of the bacterial cells, enabling ...
Published: 5/21/2019   |   Inventor(s): Sujit Datta, Tapomoy Bhattacharjee
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Category(s): Biotechnology/Pharmaceuticals

Adeno-Associated Viral Vectors Containing Alphaherpesvirus Promoter Sequences

Novel Viral Gene Therapy Vectors for Increased Genetic Payload and Long Term Chronic Expression of Therapeutic TransgenePrinceton Docket # 19-3539Researchers in Princeton University’s Neuroscience Institute and Department of Molecular Biology have developed adeno-associated viral vectors (AAV) containing promoter sequences that are small in s...
Published: 4/10/2019   |   Inventor(s): Esteban Engel, Carola Maturana, Andrew Esteves, Lynn Enquist
Keywords(s):  
Category(s): Biotechnology/Pharmaceuticals

Utilization of Human Recombinant Tinagl1 Protein in Inhibiting Triple-negative Breast Cancer Progression and Metastasis

Utilization of human recombinant Tinagl1 protein in inhibiting triple-negative-breast cancer progression and metastasis Princeton Docket # 19-3526Researchers in Princeton University’s Department of Molecular Biology have developed the human recombinant protein Tubulointerstitial nephritis antigen like-1 (Tinagl1) as a promising treatment for ...
Published: 12/21/2018   |   Inventor(s): Yibin Kang, Minhong Shen
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Category(s): Biotechnology/Pharmaceuticals

Economical and Scalable Production of Submicron Particles and Coatings at Room Temperature

Economical and Scalable Production of Submicron Particles and Coatings at Room TemperaturePrinceton Docket # 17-3329The laboratory of Prof. Howard Stone has developed a novel technology for economical and scalable synthesis and production of submicron/nano-scale and nanostructured particulate materials. The technology incorporates unique liquid ato...
Published: 11/6/2018   |   Inventor(s): Maksym Mezhericher, Howard Stone, Janine Nunes
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Category(s): Biotechnology/Pharmaceuticals, Ceramics/Material Sciences, Mechanical/Electrical Engineering

Potential Therapeutic for Arthropod-borne Flaviviruses, such as Yellow Fever, Dengue and Zika Viruses

Potential Therapeutic for Arthropod-borne Flaviviruses, such as Yellow Fever, Dengue and Zika VirusesPrinceton Docket # 18-3474Researchers in the Department of Molecular Biology have discovered a human host factor that is required for effective yellow fever virus (YFV) infection of human cells. This molecule is unlike anything, in both structure an...
Published: 11/2/2018   |   Inventor(s): Alexander Ploss, Florian Douam, Qiang Ding
Keywords(s):  
Category(s): Biotechnology/Pharmaceuticals

Predicting Genomic Variation Effects on Human Gene Transcription

De novo prediction of tissue-specific expression effect and disease risk for every mutation in a human genome - ExpectoPrinceton Docket # 18-3423Sequence-based models, with their scalability and usage of sequence dependencies, enable a new era of mutation analysis at unprecedented scale that can yield a new perspective on human variation in human d...
Published: 11/1/2018   |   Inventor(s): Olga Troyanskaya, Jian Zhou, Chandra Theesfeld
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Category(s): Biotechnology/Pharmaceuticals, Computers and Software
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