Search Results - Biotechnology/Pharmaceuticals

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Novel Method to Monitor the Viral Proteome Throughout Infection for Use in Anti-Viral Drug Discovery and Vaccine Development

Novel Method to Monitor the Viral Proteome Throughout Infection for Use in Anti-Viral Drug Discovery and Vaccine Development Princeton Docket # 20-3633 Researchers in the department of molecular biology at Princeton University have developed novel assays that use a targeted mass spectrometry approach to monitor viral proteins from all distinct temporal...
Published: 11/10/2020   |   Inventor(s): Ileana Cristea, Joel Federspiel
Keywords(s):  
Category(s): Biotechnology/Pharmaceuticals, Medical Devices/Diagnostics

Novel Small Molecule Agent for the Dispersal of Pseudomonas Aeruginosa, and other Type IV Pili Bacteria

er-collapse: collapse; } Novel Small Molecule Agent for the Dispersal of Pseudomonas Aeruginosa, and other Type IV Pili Bacteria Princeton docket # 20-3677 Researchers in the department of molecular biology, Princeton University, have identified a novel small molecule agent for the dispersal of P. Aeruginosa. Using an assay, called Dispersal...
Published: 11/4/2020   |   Inventor(s): Zemer Gitai, Robert Scheffler, Mohamed Donia, Yuki Sugimoto
Keywords(s):  
Category(s): Biotechnology/Pharmaceuticals

An Early Genetic Screening Aid in the Selection of Dogs for Assistance Training Programs

An Early Genetic Screening Aid in the Selection of Dogs for Assistance Training Programs Docket # 20-- 3609 Researchers at Princeton University and Oregon State University have conducted a genome-wide SNP study and identified genomic regions under positive selection during the initial phase of dog domestication. Deletion of one of these regions...
Published: 6/30/2020   |   Inventor(s): Bridgett Vonholdt, Monique Udell
Keywords(s):  
Category(s): Medical Devices/Diagnostics, Biotechnology/Pharmaceuticals

Antibiotic Use of Ubonodin and its Derivatives Against Burkholderia Infections

Antibiotic Use of Ubonodin and its Derivatives Against Burkholderia Infections Docket# 20-3606Researchers at Princeton University have developed a novel compound that potently kills members of the Burkholderia genus, a notorious family of bacteria that includes multiple human and plant pathogens. Many Burkholderia are resistant to conventional antibiotics,...
Published: 5/19/2020   |   Inventor(s): A. James Link, Wai Ling Cheung-Lee
Keywords(s):  
Category(s): Biotechnology/Pharmaceuticals

CO2-driven Diffusiophoresis of Colloidal Particles and Bacterial Cells

Surface contamination due to the accumulation of particles and biofilm formation causes fouling of surfaces and malfunction of devices that process particulate materials (e.g. water purifying systems and medical devices). Researchers at Princeton have invented a novel process and a method for improving existing processes for the separation of particles...
Published: 5/7/2020   |   Inventor(s): Suin Shim, Howard Stone
Keywords(s):  
Category(s): Biotechnology/Pharmaceuticals, Mechanical/Electrical Engineering

Taylorflavins and Cebulantin, Cryptic Antibiotics with Selective Antimicrobial Activity Against Gram-Negative Bacterial Pathogens

Unlocking Therapeutic Cryptic Metabolites with Bioactivity-HiTESPrinceton Docket # 20-3645Bacteria harbor an immense reservoir of potentially new and therapeutic small molecules in the form of “cryptic” biosynthetic gene clusters. These clusters can be easily identified bioinformatically, but are at best sparingly expressed under normal...
Published: 4/22/2020   |   Inventor(s): Mohammad Seyedsayamdost, Kyuho Moon
Keywords(s):  
Category(s): Biotechnology/Pharmaceuticals, Chemistry

Sequential Multi-Step Flash Nanoprecipitation for the Formation of Small Nanoparticles with High Core Loading

Flash NanoPrecipitation for Preparing High Capacity NanoparticlesPrinceton Docket # 20-3636 Researchers in the Department of Chemical and Biological Engineering at Princeton University have developed a new Flash NanoPrecipitation process, to form nanoparticles with high loadings. The new process, synthesizes nanoparticles with core loadings as...
Published: 3/10/2020   |   Inventor(s): Leon Wang, Kurt Ristroph, Robert Prud'homme
Keywords(s):  
Category(s): Biotechnology/Pharmaceuticals

An Automated System to Measure Animal Body Part Dynamics

SLEAP (Social LEAP Estimates Animal Poses): An Automated System to Measure Multi-Animal Body Part Dynamics Princeton Docket # 19-3510 Analysis of lab animal movements is a key element in a variety of behavioral studies. The current standard for analyzing animal movement relies on manual video annotation, which is time consuming, mentally...
Published: 3/3/2020   |   Inventor(s): Joshua Shaevitz, Mala Murthy, Talmo Pereira, Diego Aldarondo
Keywords(s):  
Category(s): Computers and Software, Biotechnology/Pharmaceuticals

Metabolite Stimulation to Potentiate Nitrofuran Activity in Tolerant Bacteria

Metabolite Stimulation to Potentiate Antimicrobial Nitrofurantoin Activity in Tolerant BacteriaPrinceton Docket # 20-3641-1 Researchers in the Department of Chemical and Biological Engineering at Princeton University have discovered metabolites that stimulate the susceptibility of antibiotic tolerant bacteria to the antimicrobial agent nitrofurantoin....
Published: 2/25/2020   |   Inventor(s): Mark Brynildsen, Sandra Aedo
Keywords(s):  
Category(s): Biotechnology/Pharmaceuticals

Novel High-Throughput Screening Method for Parkinson's Phenotypes Using C. elegans

Novel High-Throughput Screening Method for Parkinson’s Phenotypes Using Caenorhabditis elegansPrinceton Docket # 20-3640-1 Researchers at the Lewis-Sigler Institute for Integrative Genomics at Princeton University have developed an automated method to quantify Parkinson’s-like curling behavior in the nematode C. elegans. This method...
Published: 2/25/2020   |   Inventor(s): Coleen Murphy, Salman Sohrabi, Danielle Mor, Rachel Kaletsky, William Keyes
Keywords(s):  
Category(s): Biotechnology/Pharmaceuticals
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