A Genetically Humanized Mouse for Preclinical Testing of Specific Reagents Targeting Human CD81 and/or Occludin for study of B cell Lymphoma and Hepatitis C Docket# 19-3577-1The tetraspanin CD81, which is part of the B cell receptor complex, has emerged as an important immunotherapeutic target for treating B cell lymphoma. Researchers at Princeton University...
Published: 2/15/2024
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Inventor(s): Alexander Ploss
Keywords(s):
Category(s): Biotechnology/Pharmaceuticals
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Potential Therapeutic for Arthropod-borne Flaviviruses, such as Yellow Fever, Dengue and Zika VirusesPrinceton Docket # 18-3474Researchers in the Department of Molecular Biology have discovered a human host factor that is required for effective yellow fever virus (YFV) infection of human cells. This molecule is unlike anything, in both structure and...
Published: 2/14/2024
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Inventor(s): Alexander Ploss, Florian Douam, Qiang Ding
Keywords(s):
Category(s): Biotechnology/Pharmaceuticals
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Novel Cell Line for Hepatitis B Drug Discovery and Research
Princeton Docket # 15-3077
Researchers in the Department of Molecular Biology at Princeton University have developed a novel cell line that is susceptible to hepatitis B and delta infections (HBV, HDV). This cell culture system will allow the viruses and the host factors that modulate...
Published: 2/14/2024
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Inventor(s): Alexander Ploss, Benjamin Winer
Keywords(s): anti-infectives, anti-viral, biomarker/diagnostic, Biotechnology/Pharmaceuticals, infectious disease, life science research tools, research tool, therapeutic, vaccines, virology
Category(s): Biotechnology/Pharmaceuticals
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