Search Results - biotechnology/pharmaceuticals

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Adeno-Associated Viral Vectors Containing Alphaherpesvirus Promoter Sequences

Novel Viral Gene Therapy Vectors for Increased Genetic Payload and Long Term Chronic Expression of Therapeutic TransgenePrinceton Docket # 19-3539Researchers in Princeton University’s Neuroscience Institute and Department of Molecular Biology have developed adeno-associated viral vectors (AAV) containing promoter sequences that are small in s...
Published: 4/10/2019   |   Inventor(s): Esteban Engel, Carola Maturana, Andrew Esteves, Lynn Enquist
Keywords(s):  
Category(s): Biotechnology/Pharmaceuticals

Recombinant Phages for Targeted Bacterial Killing, Infection, Biodetection, and as a Means of Protein Extraction

Recombinant Phages for Targeted Bacterial Killing, Infection, Biodetection, and as a Means of Protein ExtractionPrinceton Docket # 19-3527Researchers in Princeton University’s Department of Molecular Biology have developed a recombinant phage platform technology that can be easily and precisely engineered for particular disease applications. ...
Published: 1/17/2019   |   Inventor(s): Justin Silpe, Bonnie Bassler
Keywords(s):  
Category(s): Biotechnology/Pharmaceuticals

Utilization of Human Recombinant Tinagl1 Protein in Inhibiting Triple-negative Breast Cancer Progression and Metastasis

Utilization of human recombinant Tinagl1 protein in inhibiting triple-negative-breast cancer progression and metastasis Princeton Docket # 19-3526Researchers in Princeton University’s Department of Molecular Biology have developed the human recombinant protein Tubulointerstitial nephritis antigen like-1 (Tinagl1) as a promising treatment for ...
Published: 12/21/2018   |   Inventor(s): Yibin Kang, Minhong Shen
Keywords(s):  
Category(s): Biotechnology/Pharmaceuticals

Economical and Scalable Production of Submicron Particles and Coatings at Room Temperature

Economical and Scalable Production of Submicron Particles and Coatings at Room TemperaturePrinceton Docket # 17-3329The laboratory of Prof. Howard Stone has developed a novel technology for economical and scalable synthesis and production of submicron/nano-scale and nanostructured particulate materials. The technology incorporates unique liquid ato...
Published: 11/6/2018   |   Inventor(s): Maksym Mezhericher, Howard Stone, Janine Nunes
Keywords(s):  
Category(s): Biotechnology/Pharmaceuticals, Ceramics/Material Sciences, Mechanical/Electrical Engineering

Potential Therapeutic for Arthropod-borne Flaviviruses, such as Yellow Fever, Dengue and Zika Viruses

Potential Therapeutic for Arthropod-borne Flaviviruses, such as Yellow Fever, Dengue and Zika VirusesPrinceton Docket # 18-3474Researchers in the Department of Molecular Biology have discovered a human host factor that is required for effective yellow fever virus (YFV) infection of human cells. This molecule is unlike anything, in both structure an...
Published: 11/2/2018   |   Inventor(s): Alexander Ploss, Florian Douam, Qiang Ding
Keywords(s):  
Category(s): Biotechnology/Pharmaceuticals

Predicting Genomic Variation Effects on Human Gene Transcription

De novo prediction of tissue-specific expression effect and disease risk for every mutation in a human genome - ExpectoPrinceton Docket # 18-3423Sequence-based models, with their scalability and usage of sequence dependencies, enable a new era of mutation analysis at unprecedented scale that can yield a new perspective on human variation in human d...
Published: 11/1/2018   |   Inventor(s): Olga Troyanskaya, Jian Zhou, Chandra Theesfeld
Keywords(s):  
Category(s): Biotechnology/Pharmaceuticals, Computers and Software

Continuous and Membrane-less Filtration of Colloidal Particulates

Continuous and Membrane-less Filtration of Colloidal Particulates Princeton Dockets # 17-3285-1, 16-3249-1 A novel method and device for separating suspended colloidal particles from aqueous stream without the use of a physical filter that is energy efficient, chemically non-invasive, and continuous. This method offers the potential to transform th...
Published: 10/25/2018   |   Inventor(s): Sangwoo Shin, Orest Shardt, Patrick Warren, Howard Stone
Keywords(s):  
Category(s): Biotechnology/Pharmaceuticals, Mechanical/Electrical Engineering, Medical Devices/Diagnostics

Immune System Activators that induce Double-stranded RNA

Immune System Activators that Induce Double-stranded RNAPrinceton Docket # 18-3436Immunotherapy is becoming an increasingly popular cancer treatment strategy that harnesses the power of the patient’s own immune system. Researchers at Princeton University have developed synthetic molecules that derepress retroviral elements in the human genome...
Published: 9/28/2018   |   Inventor(s): Alisha Chitrakar, Alexei Korennykh
Keywords(s):  
Category(s): Biotechnology/Pharmaceuticals

A High Throughput Assay for the Repurposing and Development of Drug Compounds as Novel Antibiotics

A High Throughput Assay for theRepurposing and Development of Drug Compounds as Novel AntibioticsPrinceton Docket # 15-3074The Gitai Laboratory at Princeton University has developed a high throughput assay to screen existing small molecule compound libraries to identify antibiotic activity with novel mechanisms of action. This assay can facilitate ...
Published: 6/1/2018   |   Inventor(s): Zemer Gitai, Maxwell Wilson, Hahn Kim
Keywords(s):  
Category(s): Biotechnology/Pharmaceuticals

Efficient Encapsulation of Hydrophilic Biologics into Nanocarriers

Efficient Encapsulation of Hydrophilic Biologics into NanocarriersPrinceton Docket # 18-3414-1The research team at Princeton University has demonstrated a novel and efficient method to encapsulate highly water-soluble biologic active pharmaceutical ingredients into nanocarriers using a single precipitation step.Nanoprecipitation of active pharmaceu...
Published: 5/25/2018   |   Inventor(s): Robert Prud'homme, Kurt Ristroph, Nathalie Pinkerton, Hoang (Jack) Lu
Keywords(s):  
Category(s): Biotechnology/Pharmaceuticals
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