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Docket# 14-3027-1Fluorosis, a disease caused by chronic excessive ingestion of fluoride (F-) primarily through drinking contaminated groundwater, is a major health challenge particularly in developing countries. Excess fluoride may produce several health problems such as dental fluorosis, skeletal fluorosis and various neurological manifestations. Several...
Published: 2/14/2024
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Inventor(s): Satish Myneni, Peter Jaffe
Keywords(s): Chemistry, civil engineering, earth science, green tech, polymer chemistry, wastewater management, water
Category(s): Materials
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Droplet Adhesion for Breaking an Oil-in-Water Emulsion and Phase Separation
Princeton Docket # 14-2952
Present microfluidic technologies to break emulsions or to separate phases in the emulsions include electric-field enhanced coalescence, passive-controlled coalescence, and a phase separator with embedded porous membrane. Researchers in the Department...
Published: 5/23/2022
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Inventor(s): Howard Stone, Jiang Li, Haosheng Chen, Enkai Dong
Keywords(s): Chemistry, water
Category(s): Chemistry
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Metal@Polymer Nanoparticles by Simultaneous Precipitation
and Reduction
Princeton Docket #14-3014
Researchers in the Department of Chemical and Biological Engineering at Princeton University have developed a simple one-step synergistic preparation of metal nanoparticles within spherical polymer nanoparticles through Flash NanoPrecipitation(FNP)....
Published: 4/19/2022
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Inventor(s): Rodney Priestley, Robert Prud'homme, Rui Liu, Chris Sosa
Keywords(s): catalyst, Chemistry, drug delivery, energy, Imaging, nanotechnology
Category(s): Chemistry
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Researchers at
Princeton University have synthesized a new family of robust inorganic catalysts
suitable for industrially important oxidation reactions including
electrochemical and photochemical conversion of water to hydrogen peroxide and
oxygen, and the oxidation of chloride to chlorine. Previously, there were no
commercially viable catalysts...
Published: 6/28/2022
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Inventor(s): Gerard Charles Dismukes, Wolfgang Ruettinger
Keywords(s): Chemistry
Category(s): Chemistry
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Princeton Docket # 16-3225-1Researchers in the Department of Chemical and Biological Engineering at Princeton University have developed a new method for synthesizing nanoparticles or microparticles comprised of aggregated nanoparticles having a hydrophilic core and a less polar shell. Biologically derived therapeutics, or biologics, are the most rapidly...
Published: 6/20/2024
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Inventor(s): Robert Pagels, Robert Prud'homme, Chester Markwalter
Keywords(s): Chemistry, drug delivery, Imaging
Category(s): Biotechnology/Pharmaceuticals, Medical Devices/Diagnostics
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Rapid Identification of Chemoresistance Mechanisms Using Yeast DNA Repair Mutants
Princeton Docket # 15-3160
Researchers in the Department of Molecular Biology at Princeton University have identified drug resistance mutations in key pathways in chemoresistance using the mutator phenotype of mismatch repair defective Saccharomyces cerevisiae cells and...
Published: 3/30/2022
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Inventor(s): Alison Gammie, Irene Ojini
Keywords(s): biologics, biomarker/diagnostic, Biotechnology/Pharmaceuticals, cancer/oncology, Chemistry, drug discovery, drug target, life science research tools, model organism, new molecules, platform technology, research tool, small molecule, yeast
Category(s): Biotechnology/Pharmaceuticals, Chemistry, Medical Devices/Diagnostics
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Synthetic Lethal Targeting of Mismatch Repair Defective Cells for Cancer Treatment
Princeton Docket # 15-3159
Researchers in the Department of Molecular Biology at Princeton University have developed a yeast-based high throughput chemical synthetic lethality screen to identify clinically relevant small molecules. Its application has led to the discovery...
Published: 3/30/2022
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Inventor(s): Alison Gammie, Hahn Kim, Irene Ojini
Keywords(s): biologics, biomarker/diagnostic, Biotechnology/Pharmaceuticals, cancer/oncology, Chemistry, drug discovery, drug target, new molecules, platform technology, research tool, small molecule, yeast
Category(s): Biotechnology/Pharmaceuticals, Chemistry, Medical Devices/Diagnostics
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Dual Base Metal Catalysis for Alkene and Hydrogen Production via Acceptorless and Selective Dehydrogenation of Alkanes
Princeton Docket # 15-3117
Researchers in the Department of Chemistry at Princeton University have developed a new catalyst combination, comprising of a tungsten-based polyoxometalate and cobaloxime, in order to dehydrogenate alkanes...
Published: 3/30/2022
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Inventor(s): Erik Sorensen, Julian West
Keywords(s): catalyst, Chemistry, organic synthesis, petrochemical, research tool
Category(s): Chemistry
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Phosphohistidine Mimetics for the Development of Anti-Phosphohistidine Antibodies and Identification of Therapeutic Targets
Princeton Docket # 14-2972
Researchers in the Department of Chemistry at Princeton University have developed the first phosphohistidine (pHis)-specific antibody, which has enabled the selective detection and identification of pHis...
Published: 9/12/2022
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Inventor(s): Tom Muir, Rob Oslund, Jung-Min Kee
Keywords(s): antibody, biomarker/diagnostic, Biotechnology/Pharmaceuticals, Chemistry, drug discovery, drug target, life science research tools, posttranslational modification, protein engineering, protein phosphorylation, therapeutic
Category(s): Biotechnology/Pharmaceuticals, Chemistry
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Polymer Janus Nanoparticles By Flash NanoPrecipitation
Princeton Docket # 14-2981
Janus particles are characterized by two physically distinct regions within or on the surface of the particle. Polymer Janus nanoparticles, in particular, contain at least two different polymer regions. At present, only a few ingenious routes for the generation of...
Published: 9/6/2022
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Inventor(s): Rodney Priestley, Robert Prud'homme, Chris Sosa
Keywords(s): biomarker/diagnostic, Biotechnology/Pharmaceuticals, catalyst, Chemistry, drug delivery, Imaging
Category(s): Biotechnology/Pharmaceuticals, Medical Devices/Diagnostics, Chemistry
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