Search Results - david+botstein

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Genome-Wide mapping of Polymorphisms at Nucleotide Resolution with a Single DNA Array

Princeton Invention # 06-2269 A central challenge of genomics is to detect, simply and inexpensively, any and all differences in sequence among the genomes of individual members of a species. Researchers at the Lewis-Sigler Institute for Integrative Genomics, Princeton University , have devised a system using high-density Affymetrix yeast tiling...
Published: 3/30/2022   |   Inventor(s): Leonid Kruglyak, David Botstein, David Gresham, Douglas Ruderfer, Stephen Pratt
Category(s): Biotechnology/Pharmaceuticals

Novel Gene Induction and Protein Degradation Systems: A rapid and specific tool for gene function studies and high throughput screening for target identification and drug discovery

Princeton Docket # 11-2672 Researchers at Princeton University have developed a novel system for the rapid and specific induction of individual genes, and upon modification, this system also allows for the rapid and specific degradation of target proteins. Substantial induction/degradation of target genes/proteins can be achieved within minutes...
Published: 12/15/2022   |   Inventor(s): Sanford Silverman, Robert Mcisaac, David Botstein, Marcus Noyes
Keywords(s): drug discovery, life science research tools, platform technology
Category(s): Biotechnology/Pharmaceuticals