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Novel Compounds for Treating Cholera and Other Infections: Potent Agonists of the Quorum Sensing Circuit

Princeton Dockets # 08-2418, 12-2775 & 12-2776 Cholera, an infection caused by the bacterium Vibrio cholerae, is a life-threatening disease. It is estimated that cholera affects 3-5 million people worldwide, and causes 100,000-130,000 deaths a year as of 2010. Antibiotics such as doxycycline and cotrimoxazole have been used to shorten the...
Published: 3/30/2022   |   Inventor(s): Martin Semmelhack, Bonnie Bassler, Lark Perez, Megan Bolitho, Matthew Koch, Wai-Leung Ng
Keywords(s): antibiotics, Biotechnology/Pharmaceuticals, small molecule
Category(s): Biotechnology/Pharmaceuticals