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Antibacterial Adjuvants for Reduced Cationic Antimicrobial Peptide Dosing and Combination TherapyPrinceton Docket # 20-3616-1 Researchers in the Department of Chemistry at Princeton University and the Department of Chemistry at San Jose State University have discovered compounds which increase the susceptibility of both CAP-resistant as well...
Published: 2/15/2023
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Inventor(s): Laura Conrad, Martin Semmelhack, Zinan Zhang, Minh Tran, Lauren Blankenship
Keywords(s): antibiotics
Category(s): Biotechnology/Pharmaceuticals
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Double-caged
GABA: A Novel Light-activated Probe
as a Neuroscience Research Tool
Princeton Docket #
13-2896-1
Researchers at Princeton University, Departments of Molecular
Biology and Chemistry, have developed a light-activated probe that can be used
as a neuroscience research tool.
Current methods of probing neural...
Published: 11/9/2022
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Inventor(s): Diana Shi, Samuel Wang, Martin Semmelhack
Keywords(s): Biotechnology/Pharmaceuticals, Chemistry, CNS, life science research tools
Category(s): Biotechnology/Pharmaceuticals, Chemistry
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Methods and Microfluidic Device for the Study, Testing and Treatment of Biofilm Formation in Environmental, Medical, or Industrial Devices Docket # 13-2880Researchers at Princeton University have developed a microfluidic system and method to investigate biofilm morphologies under more realistic physical conditions which could be used to screen potential...
Published: 9/8/2022
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Inventor(s): Bonnie Bassler, Howard Stone, Martin Semmelhack, Knut Drescher, Yi Shen, Colleen O'loughlin, Laura Miller Conrad
Keywords(s): antibiotics, anti-infectives, Biotechnology/Pharmaceuticals, life science research tools, medical device
Category(s): Biotechnology/Pharmaceuticals, Medical Devices/Diagnostics
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Princeton Dockets # 08-2418, 12-2775 &
12-2776
Cholera, an infection caused by the bacterium Vibrio cholerae, is a life-threatening
disease. It is estimated that
cholera affects 3-5 million people worldwide, and causes
100,000-130,000 deaths a year as of 2010. Antibiotics such as doxycycline and
cotrimoxazole have been used to shorten the...
Published: 3/30/2022
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Inventor(s): Martin Semmelhack, Bonnie Bassler, Lark Perez, Megan Bolitho, Matthew Koch, Wai-Leung Ng
Keywords(s): antibiotics, Biotechnology/Pharmaceuticals, small molecule
Category(s): Biotechnology/Pharmaceuticals
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