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C3aR as Putative Target for Inflammation

Novel C3aR agonists and antagonists for inhibiting pro-inflammatory activities of the human complement system targeting C3aR Princeton Docket # 12-2813 Novel agonists to C3aR have been designed using a de novo design framework. The best predicted peptides were experimentally validated using a rat basophilic leukemia cell degranulation assay and...
Published: 3/30/2022   |   Inventor(s): Christodoulos Floudas (DECEASED) See Fotini P. Baba, Meghan Bellows Peterson, Dimitrios Morikis, Peter Monk, Trent Woodruff
Category(s): Biotechnology/Pharmaceuticals