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Microfluidic Method for Continuous Production of Microfibers With Embedded Droplets

Microfluidic Method for Continuous Production of Microfibers with Embedded Droplets Princeton Docket #14-2982 Fibers are a useful medium for numerous applications, including drug delivery. Current technologies usually make fibers of homogeneous chemical composition or employ axial core-shell structures. To create more complex shapes and composition...
Published: 8/21/2018   |   Inventor(s): Howard Stone, Janine Nunes, Eujin Um, Tamara Pico
Keywords(s): drug delivery, life science research tools, regenerative medicine, research tool, soft scaffolds, therapeutic, tissue engineering, tissue repair, wound healing
Category(s): Medical Devices/Diagnostics

Adaptive Cognitive Prosthetic

Adaptive Cognitive Prosthetic to Treat Neurological and Neuropsychiatric Disorders and Traumatic Brain InjuriesPrinceton Docket # 14-3031A researcher in the Princeton Neuroscience Institute and the Department of Psychology at Princeton University is developing a novel treatment approach for neurological and neuropsychiatric disorders. These neural...
Published: 5/27/2015   |   Inventor(s): Timothy Buschman
Keywords(s): big data, bioinformatics, CNS, medical device, neuroscience, research tool
Category(s): Medical Devices/Diagnostics, Computers and Software

Rapid Identification of Chemoresistance Mechanisms Using Yeast DNA Repair Mutants

Rapid Identification of Chemoresistance Mechanisms Using Yeast DNA Repair Mutants Princeton Docket # 15-3160 Researchers in the Department of Molecular Biology at Princeton University have identified drug resistance mutations in key pathways in chemoresistance using the mutator phenotype of mismatch repair defective Saccharomyces cerevisiae cells ...
Published: 5/13/2015   |   Inventor(s): Alison Gammie, Irene Ojini
Keywords(s): biologics, biomarker/diagnostic, Biotechnology/Pharmaceuticals, cancer/oncology, Chemistry, drug discovery, drug target, life science research tools, model organism, new molecules, platform technology, research tool, small molecule, yeast
Category(s): Biotechnology/Pharmaceuticals, Chemistry, Medical Devices/Diagnostics

Synthetic Lethal Targeting of Mismatch Repair Defective Cells

Synthetic Lethal Targeting of Mismatch Repair Defective Cells for Cancer Treatment Princeton Docket # 15-3159 Researchers in the Department of Molecular Biology at Princeton University have developed a yeast-based high throughput chemical synthetic lethality screen to identify clinically relevant small molecules. Its application has led to the disc...
Published: 5/13/2015   |   Inventor(s): Alison Gammie, Hahn Kim, Irene Ojini
Keywords(s): biologics, biomarker/diagnostic, Biotechnology/Pharmaceuticals, cancer/oncology, Chemistry, drug discovery, drug target, new molecules, platform technology, research tool, small molecule, yeast
Category(s): Biotechnology/Pharmaceuticals, Chemistry, Medical Devices/Diagnostics

Process for Encapsulating Soluble Biologics, Therapeutics, and Imaging Agents

Process for Encapsulating Soluble Biologics, Therapeutics, and Imaging AgentsPrinceton Docket # 14-3045The encapsulation and controlled release of peptides and bio-active materials is a significant challenge in the nanoparticle field. Researchers in the Department of Chemical and Biological Engineering at Princeton University have developed a novel...
Published: 3/18/2015   |   Inventor(s): Robert Pagels, Robert Prud'homme
Keywords(s): biologics, nanotechnology, research tool
Category(s): Chemistry

Process for Acceptorless Dehydrogenation of Alkanes Through Dual Catalysis

Dual Base Metal Catalysis for Alkene and Hydrogen Production via Acceptorless and Selective Dehydrogenation of Alkanes Princeton Docket # 15-3117 Researchers in the Department of Chemistry at Princeton University have developed a new catalyst combination, comprising of a tungsten-based polyoxometalate and cobaloxime, in order to dehydrogenate alka...
Published: 2/24/2015   |   Inventor(s): Erik Sorensen, Julian West
Keywords(s): catalyst, Chemistry, organic synthesis, petrochemical, research tool
Category(s): Chemistry

Novel Cell Line for Hepatitis B Drug Discovery and Research

Novel Cell Line for Hepatitis B Drug Discovery and Research Princeton Docket # 15-3077 Researchers in the Department of Molecular Biology at Princeton University have developed a novel cell line that is susceptible to hepatitis B and delta infections (HBV, HDV). This cell culture system will allow the viruses and the host factors that modulate th...
Published: 1/14/2015   |   Inventor(s): Alexander Ploss, Benjamin Winer
Keywords(s): anti-infectives, anti-viral, biomarker/diagnostic, Biotechnology/Pharmaceuticals, infectious disease, life science research tools, research tool, therapeutic, vaccines, virology
Category(s): Biotechnology/Pharmaceuticals

Three Dimensional Multi-resolution Microscope (3DMM) for High-definition Imaging of Cell-biological Events

Docket # 13-2834-1The market for biological microscopes is greater than $1 billion annually. There is a high demand in the biomedical research field for microscopes which are capable of resolving ever smaller features and faster dynamics in live cells. However, currently available biological microscopes are limited in their ability to follow phenom...
Published: 3/14/2013   |   Inventor(s): Haw Yang, Kevin Welsher
Keywords(s): anti-infectives, anti-viral, Biotechnology/Pharmaceuticals, cancer/oncology, Imaging, life science research tools, microscopy, research tool
Category(s): Medical Devices/Diagnostics, Chemistry, Biotechnology/Pharmaceuticals

A Novel Automated Computational Method for Calculating Atomic Mappings for Chemical Reactions

A novel automated computational method for calculating atomic mappings for chemical reactions Princeton Docket # 13-2860-1 Researchers at Chemical and Biological Engineering in Princeton University have developed a novel method for computing atomic mappings for chemical reactions. Reaction mapping can be used to infer which bonds break and f...
Published: 3/5/2013   |   Inventor(s): Christodoulos Floudas (deceased) See Fotini P. Baba, Eric First, Chrysanthos Gounaris
Keywords(s): catalyst, Chemistry, computers/software, research tool
Category(s): Chemistry, Computers and Software

Microfluidic Platform for the Dynamic Regulation of Mechanical Forces on Embryonic Organs

Microfluidic Research Tool to regulate mechanical forces and properties in Branching Morphogenesis Princeton Docket # 13-2864-1 Researchers at Princeton University, Department of Chemical & Biological Engineering, have developed a microfluidic research tool to solve previously unanswered questions in the study of branching morphogenesis. ...
Published: 12/20/2012   |   Inventor(s): Jason Gleghorn, Celeste Nelson
Keywords(s): biomarker/diagnostic, medical device, research tool
Category(s): Biotechnology/Pharmaceuticals, Medical Devices/Diagnostics
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