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Microfluidic Method for Continuous Production of Microfibers with Embedded Droplets
Princeton Docket #14-2982
Fibers are a useful medium for numerous applications, including drug delivery. Current technologies usually make fibers of homogeneous chemical composition or employ axial core-shell structures. To create more complex shapes and compositions,...
Published: 3/30/2022
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Inventor(s): Howard Stone, Janine Nunes, Eujin Um, Tamara Pico
Keywords(s): drug delivery, life science research tools, regenerative medicine, research tool, soft scaffolds, therapeutic, tissue engineering, tissue repair, wound healing
Category(s): Medical Devices/Diagnostics
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Adaptive Cognitive Prosthetic to Treat Neurological and Neuropsychiatric Disorders and Traumatic Brain Injuries
Princeton Docket # 14-3031
A researcher in the Princeton Neuroscience Institute and the Department of Psychology at Princeton University is developing a novel treatment approach for neurological and neuropsychiatric disorders. These neural...
Published: 1/30/2023
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Inventor(s): Timothy Buschman
Keywords(s): big data, bioinformatics, CNS, medical device, neuroscience, research tool
Category(s): Medical Devices/Diagnostics, Computer Science and Information Technology
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Rapid Identification of Chemoresistance Mechanisms Using Yeast DNA Repair Mutants
Princeton Docket # 15-3160
Researchers in the Department of Molecular Biology at Princeton University have identified drug resistance mutations in key pathways in chemoresistance using the mutator phenotype of mismatch repair defective Saccharomyces cerevisiae cells and...
Published: 3/30/2022
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Inventor(s): Alison Gammie, Irene Ojini
Keywords(s): biologics, biomarker/diagnostic, Biotechnology/Pharmaceuticals, cancer/oncology, Chemistry, drug discovery, drug target, life science research tools, model organism, new molecules, platform technology, research tool, small molecule, yeast
Category(s): Biotechnology/Pharmaceuticals, Chemistry, Medical Devices/Diagnostics
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Synthetic Lethal Targeting of Mismatch Repair Defective Cells for Cancer Treatment
Princeton Docket # 15-3159
Researchers in the Department of Molecular Biology at Princeton University have developed a yeast-based high throughput chemical synthetic lethality screen to identify clinically relevant small molecules. Its application has led to the discovery...
Published: 3/30/2022
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Inventor(s): Alison Gammie, Hahn Kim, Irene Ojini
Keywords(s): biologics, biomarker/diagnostic, Biotechnology/Pharmaceuticals, cancer/oncology, Chemistry, drug discovery, drug target, new molecules, platform technology, research tool, small molecule, yeast
Category(s): Biotechnology/Pharmaceuticals, Chemistry, Medical Devices/Diagnostics
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Process for Encapsulating Soluble Biologics, Therapeutics, and Imaging AgentsPrinceton Docket # 14-3045The encapsulation and controlled release of peptides and bio-active materials is a significant challenge in the nanoparticle field. Researchers in the Department of Chemical and Biological Engineering at Princeton University have developed a novel...
Published: 3/17/2023
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Inventor(s): Robert Pagels, Robert Prud'homme
Keywords(s): biologics, nanotechnology, research tool
Category(s): Chemistry
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Dual Base Metal Catalysis for Alkene and Hydrogen Production via Acceptorless and Selective Dehydrogenation of Alkanes
Princeton Docket # 15-3117
Researchers in the Department of Chemistry at Princeton University have developed a new catalyst combination, comprising of a tungsten-based polyoxometalate and cobaloxime, in order to dehydrogenate alkanes...
Published: 3/30/2022
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Inventor(s): Erik Sorensen, Julian West
Keywords(s): catalyst, Chemistry, organic synthesis, petrochemical, research tool
Category(s): Chemistry
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Novel Cell Line for Hepatitis B Drug Discovery and Research
Princeton Docket # 15-3077
Researchers in the Department of Molecular Biology at Princeton University have developed a novel cell line that is susceptible to hepatitis B and delta infections (HBV, HDV). This cell culture system will allow the viruses and the host factors that modulate...
Published: 2/14/2024
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Inventor(s): Alexander Ploss, Benjamin Winer
Keywords(s): anti-infectives, anti-viral, biomarker/diagnostic, Biotechnology/Pharmaceuticals, infectious disease, life science research tools, research tool, therapeutic, vaccines, virology
Category(s): Biotechnology/Pharmaceuticals
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Docket # 13-2834-1The market for biological microscopes is greater than $1 billion annually. There is a high demand in the biomedical research field for microscopes which are capable of resolving ever smaller features and faster dynamics in live cells. However, currently available biological microscopes are limited in their ability to follow phenomena...
Published: 12/12/2022
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Inventor(s): Haw Yang, Kevin Welsher
Keywords(s): anti-infectives, anti-viral, Biotechnology/Pharmaceuticals, cancer/oncology, Imaging, life science research tools, microscopy, research tool
Category(s): Medical Devices/Diagnostics, Chemistry, Biotechnology/Pharmaceuticals
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A novel automated
computational method for calculating atomic mappings for chemical
reactions
Princeton Docket # 13-2860-1
Researchers at Chemical
and Biological Engineering in Princeton University have developed a novel
method for computing atomic mappings for chemical
reactions.
Reaction mapping can be used to infer which bonds break...
Published: 3/1/2023
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Inventor(s): Christodoulos Floudas (DECEASED) See Fotini P. Baba, Eric First, Chrysanthos Gounaris
Keywords(s): catalyst, Chemistry, computers/software, research tool
Category(s): Chemistry, Computer Science and Information Technology
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Microfluidic Research Tool to
regulate mechanical forces and properties in Branching Morphogenesis
Princeton Docket #
13-2864-1
Researchers at Princeton University, Department of
Chemical & Biological Engineering, have developed a microfluidic research
tool to solve previously unanswered questions in the study of branching
morphogenesis.
Development...
Published: 3/30/2022
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Inventor(s): Jason Gleghorn, Celeste Nelson
Keywords(s): biomarker/diagnostic, medical device, research tool
Category(s): Biotechnology/Pharmaceuticals, Medical Devices/Diagnostics
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