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Scalable, Highly Immunogenic, Polysaccharide-Peptide Nanoparticle Vaccine for Protection against Many Bacterial Serotypes

Princeton Docket # 15-3168-1Researchers in the Department of Chemical and Biological Engineering at Princeton University have developed a new nanoparticle vaccine platform which enables nanoparticle functionalization with polysaccharides and immunogenic peptides, allowing for the possibility of nanoparticle functionalization with a number of different...

Published: 7/18/2024 | Inventor(s): Nikolas Weissmueller, Robert Prud'homme, Ruth Rosenthal

Keywords(s): anti-infectives, drug delivery, nanotechnology, vaccines

Category(s): Biotechnology/Pharmaceuticals

Novel Cell Line for Hepatitis B Drug Discovery and Research

Novel Cell Line for Hepatitis B Drug Discovery and Research Princeton Docket # 15-3077 Researchers in the Department of Molecular Biology at Princeton University have developed a novel cell line that is susceptible to hepatitis B and delta infections (HBV, HDV). This cell culture system will allow the viruses and the host factors that modulate...

Published: 2/14/2024 | Inventor(s): Alexander Ploss, Benjamin Winer

Keywords(s): anti-infectives, anti-viral, biomarker/diagnostic, Biotechnology/Pharmaceuticals, infectious disease, life science research tools, research tool, therapeutic, vaccines, virology

Category(s): Biotechnology/Pharmaceuticals

A Novel Adjuvant for Improved Immunological Stimulation

Princeton Docket # 14-3007 Researchers in the Department of Molecular Biology at Princeton University have isolated a mutant strain of Escherichia coli that is specifically more resistant to vancomycin than is its wild-type parent. The resistance mutation in this strain alters an enzyme normally involved in LPS biosynthesis causing it to synthesize...

Published: 9/8/2022 | Inventor(s): Thomas Silhavy, Marcin Grabowicz, Daniel Kahne, Matthew Lebar, Dorothee Andres

Keywords(s): antibiotics, antibody, immunology, therapeutic, vaccines

Category(s): Biotechnology/Pharmaceuticals