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A facile, no carrier added method for the preparation of [18F] Drugs and Building Blocks for PET Imaging Princeton docket, # 14-3015

A facile, no carrier added method for the preparation of [18F] Drugs and Building Blocks for PET Imaging Princeton docket, # 14-3015 Princeton researchers in the department of chemistry together with colleagues at the Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital and Harvard Medical School have developed the first...

Published: 3/30/2022 | Inventor(s): John (Jay) Groves, Xiongyi Huang, Wei Liu, Jacob Hooker

Keywords(s):

Category(s): Biotechnology/Pharmaceuticals, Chemistry, Medical Devices/Diagnostics

Selective Fluorination of Drug Molecules for Higher Potency, Improved Pharmacology and Lower Metabolic Burden

Princeton Docket # 12-2797/2758-1Chemists in the laboratory of Professor John T Groves, Princeton University have discovered a powerful, simple and potentially disruptive technology for drug diversification through direct fluorination (3D-F). Fluorine is a highly desirable drug component because replacement of hydrogen with fluorine usually results...

Published: 9/27/2024 | Inventor(s): John (Jay) Groves, Wei Liu, Xiongyi Huang

Keywords(s):

Category(s): Biotechnology/Pharmaceuticals, Chemistry

Halogenation of Complex Compounds to enable Drug Diversification and Novel Small Molecules

Princeton Docket # 10-2624/2706-1 At the present time there are few, if any, ways to incorporate halogen atoms selectively into complex compounds. Halogenated organic compounds play a central role in organic chemistry, affording important components of a variety of biologically active molecules as well as pharmacologically active reagents....

Published: 11/27/2024 | Inventor(s): John (Jay) Groves, Wei Liu

Keywords(s): Biotechnology/Pharmaceuticals, drug discovery, platform technology, small molecule

Category(s): Chemistry, Biotechnology/Pharmaceuticals