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A High Throughput Screen for Molecules that Prevent the Alzheimer's Peptide Aß42 from Aggregating

Princeton Invention # 06-2246 Researchers in the Chemistry Department at Princeton University have developed a method for screening large libraries of small molecules to find those ¿hits¿ that block Aβ42 aggregation. The development of this high throughput screen is based on the finding that fusions of Aβ42 to green fluorescent...
Published: 2/14/2024   |   Inventor(s): Michael Hecht, Woojin Kim, Christine Wurth, Young-Tae Chang
Category(s): Biotechnology/Pharmaceuticals