Search Results - xiongyi+huang

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A Direct Route to Prepare Isocyanates via C-H Activation for Drug Discovery

Princeton Docket # 18-3374-1The first and only method for preparing high-valued aliphatic isocyanates via direct C-H activation has been developed by researchers at Princeton University. Organic isocyanates are versatile intermediates that provide access to a wide range of functionalities found in pharmaceuticals and agrochemicals. This method harnesses...
Published: 11/13/2017   |   Inventor(s): John (Jay) Groves, Xiongyi Huang, Thompson Zhuang
Keywords(s):  
Category(s): Biotechnology/Pharmaceuticals, Chemistry

A facile, no carrier added method for the preparation of [18F] Drugs and Building Blocks for PET Imaging Princeton docket, # 14-3015

A facile, no carrier added method for the preparation of [18F] Drugs and Building Blocks for PET Imaging Princeton docket, # 14-3015 Princeton researchers in the department of chemistry together with colleagues at the Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital and Harvard Medical School have developed the first...
Published: 6/30/2014   |   Inventor(s): John (Jay) Groves, Xiongyi Huang, Wei Liu, Jacob Hooker
Keywords(s):  
Category(s): Biotechnology/Pharmaceuticals, Chemistry, Medical Devices/Diagnostics

Selective Fluorination of Drug Molecules for Higher Potency, Improved Pharmacology and Lower Metabolic Burden

Princeton Docket # 12-2797/2758-1Chemists in the laboratory of Professor John T Groves, Princeton University have discovered a powerful, simple and potentially disruptive technology for drug diversification through direct fluorination (3D-F). Fluorine is a highly desirable drug component because replacement of hydrogen with fluorine usually results...
Published: 3/21/2013   |   Inventor(s): John (Jay) Groves, Wei Liu, Xiongyi Huang
Keywords(s):  
Category(s): Biotechnology/Pharmaceuticals, Chemistry