Search Results - zemer+gitai

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Method of Assessing Bacterial Viability on Low Biomass Environments

Method of Assessing Bacterial Viability on Low Biomass EnvironmentsPrinceton Docket # 22-3843 Researchers in the Department of Molecular Biology, Princeton University have developed a novel method of assessing bacterial community viability. This highly reliable and accurate method allows for the assessment of extremely low biomass samples, which cannot...
Published: 9/9/2022   |   Inventor(s): Zemer Gitai, Ellen Acosta
Keywords(s):  
Category(s): Biotechnology/Pharmaceuticals, Medical Devices/Diagnostics

Novel Small Molecule Agent for the Dispersal of Pseudomonas Aeruginosa, and other Type IV Pili Bacteria

er-collapse: collapse; } Novel Small Molecule Agent for the Dispersal of Pseudomonas Aeruginosa, and other Type IV Pili Bacteria Princeton docket # 20-3677 Researchers in the department of molecular biology, Princeton University, have identified a novel small molecule agent for the dispersal of P. Aeruginosa. Using an assay, called Dispersal...
Published: 9/9/2022   |   Inventor(s): Zemer Gitai, Robert Scheffler, Mohamed Donia, Yuki Sugimoto
Keywords(s):  
Category(s): Biotechnology/Pharmaceuticals

Inhibiting Bacteria Infection in Healthcare Devices through Surface Chemistry Treatments and Fluid Flow Control

Princeton Docket # 15-3109-1Researchers in the Departments of Molecular Biology and Mechanical and Aerospace Engineering at Princeton University have designed new methods to effectively inhibit the entry, spread and growth of bacteria. The entry of pathogenic bacteria into fluid-filled networks of the body causes serious infection and sepsis. In particular,...
Published: 2/14/2024   |   Inventor(s): Howard Stone, Zemer Gitai, Min Kim, Yi Shen, Albert Siryaporn
Keywords(s):  
Category(s): Medical Devices/Diagnostics

A High Throughput Assay for the Repurposing and Development of Drug Compounds as Novel Antibiotics

A High Throughput Assay for theRepurposing and Development of Drug Compounds as Novel AntibioticsPrinceton Docket # 15-3074The Gitai Laboratory at Princeton University has developed a high throughput assay to screen existing small molecule compound libraries to identify antibiotic activity with novel mechanisms of action. This assay can facilitate the...
Published: 1/13/2023   |   Inventor(s): Zemer Gitai, Maxwell Wilson, Hahn Kim, Hsin-Jung Li, James Martin
Keywords(s):  
Category(s): Biotechnology/Pharmaceuticals

Blocking bacterial infection by inhibiting surface-regulated virulence induction

Princeton Docket # 15-3090Researchers in the Department of Molecular Biology at Princeton University and the School of Medicine at Dartmouth College have identified a novel strategy for inhibiting the pathogenesis of the human pathogen Pseudomonas aeruginosa by regulating its virulence factors upon surface contact instead of inhibiting its growth. ...
Published: 3/30/2022   |   Inventor(s): Zemer Gitai, Albert Siryaporn, George O'toole, Sherry Kuchma
Keywords(s): antibiotics, biomarker/diagnostic, Biotechnology/Pharmaceuticals, drug discovery, infectious disease, life science research tools, small molecule, therapeutic
Category(s): Biotechnology/Pharmaceuticals, Chemistry, Medical Devices/Diagnostics