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DNA Valency Sorting Chromatography for Separating Large Solutes

­ DNA Valency Sorting Chromatography for Separating Large Solutes Princeton Docket # 22-3863 Few technologies are available for analyzing or purifying, in a general way, large solutes labeled with a defined number of molecules. Large solutes could be organic or inorganic nanoparticles, large macromolecules, assemblies of macromolecules or nanoparticles,...
Published: 9/8/2022   |   Inventor(s): Haw Yang, Nyssa Emerson
Keywords(s):  
Category(s): Chemistry, Biotechnology/Pharmaceuticals

Glycopeptide Antibiotic Combination Therapy Against Clostridial Infections, In Particular, C difficile

Glycopeptide Antibiotic Combination Therapy Against Clostridial Infections, In Particular, C. difficilePrinceton Docket # 21-3813Researchers in the Department of Chemistry, Princeton University, and the Department of Chemistry, Emory University, have identified that when combined, vancomycin and keratinicyclin B interact synergistically to inhibit the...
Published: 11/21/2022   |   Inventor(s): Mohammad Seyedsayamdost, Vasiliki Chioti, Katherine Davis, Kirklin McWhorter
Keywords(s):  
Category(s): Biotechnology/Pharmaceuticals, Chemistry

Tryglysin A and B Novel, Selective, and Potent Antibacterial Agents Against Streptococcus Bacteria

Tryglysin A and B, Novel, Selective, and Potent Antibacterial Agents Against Streptococcus BacteriaPrinceton Docket # 21-3758Researchers in the Department of Chemistry at Princeton University and the Department of Pharmaceutical Sciences at the University of Illinois at Chicago have identified novel small organic molecules with potent and highly selective...
Published: 9/8/2022   |   Inventor(s): Mohammad Seyedsayamdost, Michael Federle, Brett Covington, Leah Bushin, Britta Rued, John Ambrose
Keywords(s):  
Category(s): Chemistry, Biotechnology/Pharmaceuticals

Human IDO1- Selective Agonists for Treating Autoimmune Disorders

IDO1 Selective Agonists for Treating Autoimmune Disorders Docket # 19-3557The Groves lab in the Department of Chemistry at Princeton University has identified a new pathway in suppressing immune responses which may lead to novel compounds for treating autoimmune diseases. Proof of concept and a lead compound have been identified allowing for the...
Published: 9/13/2022   |   Inventor(s): John (Jay) Groves, Micah Nelp
Keywords(s):  
Category(s): Biotechnology/Pharmaceuticals, Chemistry

Taylorflavins and Cebulantin, Cryptic Antibiotics with Selective Antimicrobial Activity Against Gram-Negative Bacterial Pathogens

Unlocking Therapeutic Cryptic Metabolites with Bioactivity-HiTESPrinceton Docket # 20-3645Bacteria harbor an immense reservoir of potentially new and therapeutic small molecules in the form of “cryptic” biosynthetic gene clusters. These clusters can be easily identified bioinformatically, but are at best sparingly expressed under normal...
Published: 9/8/2022   |   Inventor(s): Mohammad Seyedsayamdost, Kyuho Moon
Keywords(s):  
Category(s): Biotechnology/Pharmaceuticals, Chemistry

Bioremediation of Halogenated Organics (PFAS), Aromatic Hydrocarbons, Radionuclides, and Ammonium

Bioremediation of Halogenated Organics (PFAS), Aromatic Hydrocarbons, Radionuclides, and AmmoniumPrinceton Dockets # 15-3080/2918-1, 18-3400-1, 19-3515-1, 19-3517-1A novel anaerobic bioremediation system capable of:1) Energy efficient anaerobic ammonium removal, at lower temperature than Anammox2) Degrading wide range of organic pollutants,...
Published: 3/30/2022   |   Inventor(s): Peter Jaffe, Shan Huang, Emily Gilson
Keywords(s): civil engineering, metal reduction, wastewater management, water
Category(s): Chemistry

Green and Safe Electrolytes for Multivalent-Ion (Mg, Ca, etc.) Batteries

Green and Safe Electrolytes for Multivalent-Ion (Mg, Ca, etc.) BatteriesPrinceton Docket # 15-3142/3143/16-3237Prof. Craig Arnold’s laboratory has developed a green and halide free electrolyte system for multivalent-ion (Mg, Ca, and others) batteries capable of reversible metal electrodeposition that is superior to current chemistries that utilize...
Published: 3/30/2022   |   Inventor(s): Jake Herb, Craig Arnold, Carl Nist-Lund
Keywords(s):  
Category(s): Chemistry, Ceramics/Material Sciences

Droplet Adhesion for Breaking Oil-In-Water Emulsion and Phase Separation

Droplet Adhesion for Breaking an Oil-in-Water Emulsion and Phase Separation Princeton Docket # 14-2952 Present microfluidic technologies to break emulsions or to separate phases in the emulsions include electric-field enhanced coalescence, passive-controlled coalescence, and a phase separator with embedded porous membrane. Researchers in the Department...
Published: 5/23/2022   |   Inventor(s): Howard Stone, Jiang Li, Haosheng Chen, Enkai Dong
Keywords(s): Chemistry, water
Category(s): Chemistry

Rapid and High Yield Reduction of CO2 to Commercially Valuable Multi Carbon Products

Rapid and High Yield Reduction of CO2 to Commercially Valuable Multi Carbon ProductsPrinceton Docket # 18-3372-1The laboratory of Prof. Andrew Bocarsly has created a collection of alloy electrodes capable of reducing CO2 to high value multi-carbon products in a fast, efficient, and high yield manner that is industrially attractive for CO2 utilization....
Published: 9/8/2022   |   Inventor(s): Aubrey Paris, Sonja Francis, An Chu, Andrew Bocarsly
Keywords(s):  
Category(s): Chemistry

DEEPs - De novo Expression Enhancer Proteins for Improved Protein Expression and Purification

Princeton Docket # 17-3357-1To improve the production of biomedically important peptides and proteins that are challenging to express with recombinant DNA technology, researchers at Princeton University have created a collection of synthetic genes to encode highly stable de novo proteins for use as genetic fusion tags. The resulting method has been...
Published: 9/8/2022   |   Inventor(s): Michael Hecht, Shlomo Zarzhitsky
Keywords(s):  
Category(s): Chemistry, Biotechnology/Pharmaceuticals
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