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Search Results - manav+korpal
miR-200 Family and miR194/192 Cluster of miRNAs in Cancer Progression and Metastasis
Princeton University Invention # 09-2551 Over 90% of cancer-related deaths are due to the metastatic spread of primary tumor cells to distant vital organs. Epithelial-mesenchymal transition (EMT) is a key cellular process through which tumor cells gain the ability to migrate and invade into their surrounding tissue. The reverse process, (MET),...
Novel Therapeutics for Cancer Metastasis
Princeton Docket # 11-2691-1 Using various in vitro and in vivo xenograft model systems and clinical samples, researchers in the department of molecular biology, Princeton University have validated a stage-specific functional role of the miR-200 family to tumor progression. Current studies suggest that the miR-200 family may hinder an early step...