Search Results - metabolic+engineering

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ClpP is a Major Regulator in NO Stressed E Coli

Discovery of ClpP Protein, a Major Regulator in Nitric Oxide Stressed Escherichia coli, for Anti-infective Development Strategies Princeton Docket # 15-3064 Antibiotic resistance has become a public health crisis, while the rate of new antibiotic development declines. A promising solution is antivirulence therapy, which targets host-pathogen interactions,...
Published: 12/21/2022   |   Inventor(s): Mark Brynildsen, Jonathan Robinson
Keywords(s): antibiotics, anti-infectives, biomarker/diagnostic, life science research tools, metabolic engineering, protein engineering
Category(s): Biotechnology/Pharmaceuticals, Chemistry

Production of Biofuels, Biomaterials and Sugar Alcohols (Polyols) by a Recombinant Microorganism Expressing Enzymes (Det1 and Pho13) for NADPH Upregulation and Polyol Phosphatase (Ynl010w) for Polyol Phosphatase Dephosphorylation

A New Enzyme and Process for Metabolic Engineering of Production of Sorbitol, Mannitol, Ribitol, Xylitol, Arabitol, Erythritol, and Other Polyols Princeton Docket # 13-2939 Scientists in the Lewis-Sigler Institute, Princeton University have discovered an enzyme which encodes a broad-spectrum, D-stereoisomer-specific sugar alcohol phosphatase,...
Published: 11/7/2022   |   Inventor(s): Yi-Fan Xu, Joshua Rabinowitz, Fabien Letisse, Sarah Johnson
Keywords(s): biofuels, Biotechnology/Pharmaceuticals, Chemistry, metabolic engineering, model organism, yeast
Category(s): Biotechnology/Pharmaceuticals