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Novel Lasso Peptides as Molecular Scaffolds for Protein Therapeutics, Molecular Sensors and Probes

Researchers at Princeton University, in the Department of Chemical and Biological Engineering, have engineered a gene cluster which encodes for the biosynthesis of a natural peptide product called Astexin-1. Astexin-1 is a new member of the lasso peptide class. Molecules of this class are highly stable, engineerable and may be utilized as molecular...

Published: 9/13/2022 | Inventor(s): Aaron James Link, Mikhail Maksimov

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Category(s): Biotechnology/Pharmaceuticals