Search Results - thomas+shenk

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Sirt4 Lipoamidase Activity and Uses Thereof

A Novel Assay for Sirtuin 4 (SIRT4) Lipoamidase Activity and the Activity of the Pyruvate Dehydrogenase Complex Princeton Docket # 14-3002 A novel assay for measuring the lipoamidase activity of SIRT4 in mammalian cells and tissue samples has been created. A procedure by which the lipoamide cofactor activity can be monitored in mammalian cells has...
Published: 10/28/2022   |   Inventor(s): Thomas Shenk, Todd Greco, Ileana Cristea, Rommel Mathias, Adam Oberstein
Keywords(s): biologics, Biotechnology/Pharmaceuticals, genomics/proteomics (software), virology
Category(s): Biotechnology/Pharmaceuticals, Chemistry, Medical Devices/Diagnostics

microRNAs for Modulating Herpes Virus Gene Expression

Princeton University Invention # 07-2381 Researchers in the Molecular Biology department at Princeton University and the Simons Center for Systems Biology at the Institute for Advanced Study have developed an improved algorithm for the prediction of mRNAs that are targeted by known microRNAs. The algorithm was employed to identify...
Published: 3/30/2022   |   Inventor(s): Thomas Shenk, Arnold Levine, Jiri Vanicek, Eain Murphy, Harlan Robins
Category(s): Biotechnology/Pharmaceuticals

Recombinant Adeno-Associated Viruses for use in Gene Therapy

Princeton University Invention # 90-0954 The technology as described in US patent # 5,753,500 relates to a method for producing substantially pure stocks of recombinant adeno-associated virus, free of the adeno-associated helper virus found associated with previously available recombinant AAV. These pure stocks can be used to introduce exogenous...
Published: 6/22/2022   |   Inventor(s): Mark Labow, Stephan Baim, Arnold Levine, Thomas Shenk
Category(s): Biotechnology/Pharmaceuticals