Search Results - ihor+lemischka

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Programmed Autoregulation of Stem Cell Differentiation into Pancreatic Beta cell: Potential Treatment for Diabetes

Princeton Docket # 07-2347 Researchers in Electrical Engineering and Molecular Biology, Princeton University have developed new levels of controlled differentiation in embryonic stem cells that are well-beyond existing technologies. The proposed approach will lead to new opportunities and strategies in many different biomedical therapies, such...
Published: 9/26/2022   |   Inventor(s): Ronald Weiss, Ihor Lemischka, Christoph Schaniel, Priscilla Purnick, Miles Miller, Patrick Guye
Keywords(s): diabetes, stem cell
Category(s): Biotechnology/Pharmaceuticals

New Simple Tools, NeFRECs, for Large Scale Screens Using Small Molecules and Genomic Libraries in Stem Cell Biology and Nuclear Reprogramming

Princeton University Invention # 05-2180 Molecular mechanisms regulating the identity of stem cells and their balance of self-renewal and differentiation are critical for proper tissue development of every organism and the development of regenerative cell therapies. Embryonic stem cell-based therapies bear some potential but are very controversial....
Published: 3/30/2022   |   Inventor(s): Ihor Lemischka, Christoph Schaniel, Feng Li, Xenia Schafer
Keywords(s):  
Category(s): Biotechnology/Pharmaceuticals

METHOD FOR GENETIC ANALYSIS OF ALTERNATIVE SPLICING

Researchers at Princeton University have developed methods useful in genetic high-throughput screens (HTS) of alternative splice variants. More specifically, the developed technology can be applied for massive functional identification of splice variants whose misexpression can promote cancerous cell transformation or induce stem cell differentiation...
Published: 10/12/2022   |   Inventor(s): Ihor Lemischka, Moshe Pritsker
Keywords(s):  
Category(s): Biotechnology/Pharmaceuticals

METHOD FOR ANALYSIS OF GENETIC INTERACTIONS

Researchers at Princeton University have developed methods useful in large-scale probing of interactions between genes and their products. More specifically, the new technology is useful for a systematic parallel analysis of genetic and protein-protein interactions on a genome-wide scale. For example, the developed technology can be applied for...
Published: 3/30/2022   |   Inventor(s): Ihor Lemischka, Moshe Pritsker
Keywords(s):  
Category(s): Biotechnology/Pharmaceuticals