Search Results - mohammad+seyedsayamdost

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Metabolomics Explorer (MetEx) for Cryptic Natural Products or Antibiotic Drug Discovery

Metabolomics Explorer (MetEx) for Cryptic Natural Product or Antibiotic Drug DiscoveryPrinceton Docket # 22-3873Researchers in Princeton University’s Department of Chemistry have developed Metabolomics Explorer (MetEx), an application for the analysis of parallel liquid chromatography-coupled mass spectrometry (LC-MS)-based metabolomics data....
Published: 12/8/2021   |   Inventor(s): Mohammad Seyedsayamdost, Brett Covington
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Category(s): Biotechnology/Pharmaceuticals

Glycopeptide Antibiotic Combination Therapy Against Clostridial Infections, In Particular, C difficile

Glycopeptide Antibiotic Combination Therapy Against Clostridial Infections, In Particular, C. difficilePrinceton Docket # 21-3813Researchers in the Department of Chemistry, Princeton University, and the Department of Chemistry, Emory University, have identified that when combined, vancomycin and keratinicyclin B interact synergistically to inhibit the...
Published: 9/24/2021   |   Inventor(s): Mohammad Seyedsayamdost, Vasiliki Chioti, Katherine Davis, Kirklin McWhorter
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Category(s): Biotechnology/Pharmaceuticals, Chemistry

Tryglysin A and B Novel, Selective, and Potent Antibacterial Agents Against Streptococcus Bacteria

Tryglysin A and B, Novel, Selective, and Potent Antibacterial Agents Against Streptococcus BacteriaPrinceton Docket # 21-3758Researchers in the Department of Chemistry at Princeton University and the Department of Pharmaceutical Sciences at the University of Illinois at Chicago have identified novel small organic molecules with potent and highly selective...
Published: 7/14/2021   |   Inventor(s): Mohammad Seyedsayamdost, Michael Federle, Brett Covington, Leah Bushin, Britta Rued, John Ambrose
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Category(s): Chemistry, Biotechnology/Pharmaceuticals

Taylorflavins and Cebulantin, Cryptic Antibiotics with Selective Antimicrobial Activity Against Gram-Negative Bacterial Pathogens

Unlocking Therapeutic Cryptic Metabolites with Bioactivity-HiTESPrinceton Docket # 20-3645Bacteria harbor an immense reservoir of potentially new and therapeutic small molecules in the form of “cryptic” biosynthetic gene clusters. These clusters can be easily identified bioinformatically, but are at best sparingly expressed under normal...
Published: 4/22/2020   |   Inventor(s): Mohammad Seyedsayamdost, Kyuho Moon
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Category(s): Biotechnology/Pharmaceuticals, Chemistry

Guanfacine as an Anti-Virulence Agent in Pseudomonas Aeruginosa

Guanfacine as an Anti-Virulence Agent in Pseudomonas aeruginosaDocket# 19-3565-1Current anti-infective therapies against bacterial pathogens fall in two broad categories: vaccines and antibiotics. While vaccines serve in disease prevention, antibiotics kill pathogens after infection. However, since antibiosis creates a selective pressure for resistant...
Published: 7/15/2019   |   Inventor(s): Mohammad Seyedsayamdost, Bethany Okada, Anran Li
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Category(s): Biotechnology/Pharmaceuticals

Keratinimicins and Keratinicyclins- Novel families of antibacterial and antiviral agents

Keratinimicins and Keratinicyclins- Novel families of antibacterial and antiviral agentsDocket# 18-3381-1Researchers at Princeton University have developed a rapid genetics-free method for eliciting and detecting cryptic metabolites. Utilizing this approach, the inventors have activated production of diverse cryptic metabolites and characterized several...
Published: 7/15/2019   |   Inventor(s): Mohammad Seyedsayamdost, Fei Xu, Yihan Wu, Leah Bushin, Katherine Davis
Keywords(s):  
Category(s): Biotechnology/Pharmaceuticals