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EGFR Inhibitors as Therapeutic Agents for Breast Cancer Bone Metastasis Princeton University Invention # 09-2509 The involvement of the EGFR signaling pathway in bone metastasis has been implicated by a number of studies. However, the therapeutic significance by targeting EGFR signaling in the tumor-stroma interface has not been evaluated. Researchers in the Molecular Biology Department at Princeton... Published: 3/30/2022   |   Inventor(s): Yibin Kang, Xin Lu Keywords(s): antibody, cancer/oncology, therapeutic Category(s): Biotechnology/Pharmaceuticals

VCAM1 and VLA4 as Therapeutic Targets for Anti-Tumor and Anti Metastatic Therapy Princeton University Invention # 09-2550 In breast cancer patients, disseminated tumor cells from the primary site can remain in a dormant state in the secondary organ for a long period before starting to grow into life-threatening metastasis. However, the molecular understanding of this process is still very limited. Researchers in Molecular... Published: 3/30/2022   |   Inventor(s): Yibin Kang, Xin Lu Keywords(s):   Category(s): Biotechnology/Pharmaceuticals