Search Results - robert+prud%27homme

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Sequential Multi-Step Flash Nanoprecipitation for the Formation of Small Nanoparticles with High Core Loading

Flash NanoPrecipitation for Preparing High Capacity NanoparticlesPrinceton Docket # 20-3636 Researchers in the Department of Chemical and Biological Engineering at Princeton University have developed a new Flash NanoPrecipitation process, to form nanoparticles with high loadings. The new process, synthesizes nanoparticles with core loadings as...

Published: 9/6/2022 | Inventor(s): Leon Wang, Kurt Ristroph, Robert Prud'homme

Keywords(s):

Category(s): Biotechnology/Pharmaceuticals

Efficient Encapsulation of Hydrophilic Biologics into Nanocarriers

Efficient Encapsulation of Hydrophilic Biologics into NanocarriersPrinceton Docket # 18-3414-1The research team at Princeton University has demonstrated a novel and efficient method to encapsulate highly water-soluble biologic active pharmaceutical ingredients into nanocarriers using a single precipitation step.Nanoprecipitation of active pharmaceutical...

Published: 2/4/2025 | Inventor(s): Robert Prud'homme, Kurt Ristroph, Nathalie Pinkerton, Hoang (Jack) Lu, Paradorn Rummaneethorn

Keywords(s):

Category(s): Biotechnology/Pharmaceuticals

An Economical Design and Processing of Lipophilic Drugs for Fast-Releasing Water Dispersible Formulations

An Economical Design and Processing of Lipophilic Drugs for Fast-Releasing Water Dispersible FormulationsPrinceton Docket # 18-3396-1The Prud’homme group has developed a novel, economical, and scalable formulation and process to prepare nanoparticles from poorly water soluble drugs in order to improve oral bioavailability and dissolution rate...

Published: 2/4/2025 | Inventor(s): Jie Feng, Kurt Ristroph, Hoang Lu, Yingyue Zhang, Simon McManus, Robert Prud'homme

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Category(s): Biotechnology/Pharmaceuticals

Metal@Polymer Nanoparticles by Simultaneous Precipitation and Reduction

Metal@Polymer Nanoparticles by Simultaneous Precipitation and Reduction Princeton Docket #14-3014 Researchers in the Department of Chemical and Biological Engineering at Princeton University have developed a simple one-step synergistic preparation of metal nanoparticles within spherical polymer nanoparticles through Flash NanoPrecipitation(FNP)....

Published: 4/15/2025 | Inventor(s): Rodney Priestley, Robert Prud'homme, Rui Liu, Chris Sosa

Keywords(s): catalyst, Chemistry, drug delivery, energy, Imaging, nanotechnology

Category(s): Chemistry

Scalable, Highly Immunogenic, Polysaccharide-Peptide Nanoparticle Vaccine for Protection against Many Bacterial Serotypes

Princeton Docket # 15-3168-1Researchers in the Department of Chemical and Biological Engineering at Princeton University have developed a new nanoparticle vaccine platform which enables nanoparticle functionalization with polysaccharides and immunogenic peptides, allowing for the possibility of nanoparticle functionalization with a number of different...

Published: 7/18/2024 | Inventor(s): Nikolas Weissmueller, Robert Prud'homme, Ruth Rosenthal

Keywords(s): anti-infectives, drug delivery, nanotechnology, vaccines

Category(s): Biotechnology/Pharmaceuticals

Highly loaded (Depot) Microparticle Delivery System for the Controlled Release of Aqueous Soluble Biologics and Therapeutics

Princeton Docket # 16-3225-1Researchers in the Department of Chemical and Biological Engineering at Princeton University have developed a new method for synthesizing nanoparticles or microparticles comprised of aggregated nanoparticles having a hydrophilic core and a less polar shell. Biologically derived therapeutics, or biologics, are the most rapidly...

Published: 2/19/2025 | Inventor(s): Robert Pagels, Robert Prud'homme, Chester Markwalter

Keywords(s): Chemistry, drug delivery, Imaging

Category(s): Biotechnology/Pharmaceuticals, Medical Devices/Diagnostics

Nano-Encapsulation Using GRAS Materials

Nanoparticle Compositions and Methods using Gras Materials for encapsulation and delivery of active pharmaceutical ingredients Princeton Docket # 15-3169Researchers in the Department of Chemical and Biological Engineering at Princeton University have developed a new nano-encapsulation process using generally recognized as safe (GRAS) material. Through...

Published: 2/25/2025 | Inventor(s): Nikolas Weissmueller, Robert Prud'homme

Keywords(s):

Category(s): Biotechnology/Pharmaceuticals

Enhanced Adjunctive Therapies for Microbial Infections and Imaging

Princeton Docket # 16-3183-1Researchers in the Department of Chemical and Biological Engineering at Princeton University have developed a nanocarrier based approach to enable and enhance adjunctive therapies for microbial infections by simultaneous encapsulation and delivery of all components.Microbial infections have become increasingly difficult to...

Published: 9/11/2024 | Inventor(s): Robert Prud'homme, Hoang Lu

Keywords(s): antibiotics, drug delivery, Imaging, nanotechnology

Category(s): Biotechnology/Pharmaceuticals

Process for Encapsulating Soluble Biologics, Therapeutics, and Imaging Agents

Process for Encapsulating Soluble Biologics, Therapeutics, and Imaging AgentsPrinceton Docket # 14-3045The encapsulation and controlled release of peptides and bio-active materials is a significant challenge in the nanoparticle field. Researchers in the Department of Chemical and Biological Engineering at Princeton University have developed a novel...

Published: 4/2/2025 | Inventor(s): Robert Pagels, Robert Prud'homme

Keywords(s): biologics, nanotechnology, research tool

Category(s): Chemistry

Polymer Janus Nanoparticles by Flash NanoPrecipitation

Polymer Janus Nanoparticles By Flash NanoPrecipitation Princeton Docket # 14-2981 Janus particles are characterized by two physically distinct regions within or on the surface of the particle. Polymer Janus nanoparticles, in particular, contain at least two different polymer regions. At present, only a few ingenious routes for the generation...

Published: 4/15/2025 | Inventor(s): Rodney Priestley, Robert Prud'homme, Chris Sosa

Keywords(s): biomarker/diagnostic, Biotechnology/Pharmaceuticals, catalyst, Chemistry, drug delivery, Imaging

Category(s): Biotechnology/Pharmaceuticals, Medical Devices/Diagnostics, Chemistry

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