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Identification of Novel Isoforms of a Gene and Their Potential Utility in Diagnostic and Therapeutic Applications

Identification of Novel Isoforms of a Gene and Their Potential Utility in Diagnostic and Therapeutic Applications in Diseases of Cellular Motility, Migration, and/or Invasion Princeton Docket # 13-2929-1 High throughput sequencing approaches have revealed increased complexity of the transcriptome. For example, one gene may give rise to multiple mRNAs...
Published: 3/30/2022   |   Inventor(s): Hilary Coller, David Corney
Keywords(s): biomarker/diagnostic, cancer/oncology, life science research tools, therapeutic
Category(s): Biotechnology/Pharmaceuticals, Medical Devices/Diagnostics

Inducing apoptosis in quiescent cells, a potential new therapeutic strategy for chemotherapy and the treatment of fibrotic disease

Princeton Docket # 11-2633 The ability to selectively kill quiescent cells could be a powerful tool in medicine. In particular, the ability to kill the quiescent tumor stem cells could be an important addition to our chemotherapeutic repertoire. A better understanding of the transition between quiescent and activated cellular states of fibroblasts...
Published: 3/30/2022   |   Inventor(s): Hilary Coller
Keywords(s): cancer/oncology, drug discovery, small molecule
Category(s): Biotechnology/Pharmaceuticals