Search Results - colleen+o%27loughlin

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Microfluidic Device for the Study and Treatment of Biofilm Formation in Environmental, Medical, or Industrial Devices

Methods and Microfluidic Device for the Study, Testing and Treatment of Biofilm Formation in Environmental, Medical, or Industrial Devices Docket # 13-2880Researchers at Princeton University have developed a microfluidic system and method to investigate biofilm morphologies under more realistic physical conditions which could be used to screen potential...
Published: 9/8/2022   |   Inventor(s): Bonnie Bassler, Howard Stone, Martin Semmelhack, Knut Drescher, Yi Shen, Colleen O'loughlin, Laura Miller Conrad
Keywords(s): antibiotics, anti-infectives, Biotechnology/Pharmaceuticals, life science research tools, medical device
Category(s): Biotechnology/Pharmaceuticals, Medical Devices/Diagnostics

Resistant-Prone Small Molecule Anti-Bacterial Antagonists and Targets for Anti-Bacterial Drug Development

Princeton Docket # 08-2467 & 08-2486 Researchers at Princeton University, Department of Molecular Biology, have identified and synthesized small molecule antagonists that could serve as broad spectrum lead compounds for the disruption of quorum sensing in pathogenic Gram-negative bacteria. In proof of principle experiments, potent antagonist...
Published: 9/19/2022   |   Inventor(s): Bonnie Bassler, Lee Swem, Scott Ulrich, Colleen O'loughlin
Keywords(s): antibiotics, drug target, small molecule
Category(s): Biotechnology/Pharmaceuticals