Search Results - drug+delivery

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Microfluidic Method for Continuous Production of Microfibers With Embedded Droplets

Microfluidic Method for Continuous Production of Microfibers with Embedded Droplets Princeton Docket #14-2982 Fibers are a useful medium for numerous applications, including drug delivery. Current technologies usually make fibers of homogeneous chemical composition or employ axial core-shell structures. To create more complex shapes and compositions,...
Published: 3/30/2022   |   Inventor(s): Howard Stone, Janine Nunes, Eujin Um, Tamara Pico
Keywords(s): drug delivery, life science research tools, regenerative medicine, research tool, soft scaffolds, therapeutic, tissue engineering, tissue repair, wound healing
Category(s): Medical Devices/Diagnostics

Metal@Polymer Nanoparticles by Simultaneous Precipitation and Reduction

Metal@Polymer Nanoparticles by Simultaneous Precipitation and Reduction Princeton Docket #14-3014 Researchers in the Department of Chemical and Biological Engineering at Princeton University have developed a simple one-step synergistic preparation of metal nanoparticles within spherical polymer nanoparticles through Flash NanoPrecipitation(FNP)....
Published: 4/19/2022   |   Inventor(s): Rodney Priestley, Robert Prud'homme, Rui Liu, Chris Sosa
Keywords(s): catalyst, Chemistry, drug delivery, energy, Imaging, nanotechnology
Category(s): Chemistry

Scalable, Highly Immunogenic, Polysaccharide-Peptide Nanoparticle Vaccine for Protection against Many Bacterial Serotypes

Princeton Docket # 15-3168-1Researchers in the Department of Chemical and Biological Engineering at Princeton University have developed a new nanoparticle vaccine platform which enables nanoparticle functionalization with polysaccharides and immunogenic peptides, allowing for the possibility of nanoparticle functionalization with a number of different...
Published: 2/14/2024   |   Inventor(s): Nikolas Weissmueller, Robert Prud'homme, Ruth Rosenthal
Keywords(s): anti-infectives, drug delivery, nanotechnology, vaccines
Category(s): Biotechnology/Pharmaceuticals

Highly loaded (Depot) Microparticle Delivery System for the Controlled Release of Aqueous Soluble Biologics and Therapeutics

Princeton Docket # 16-3225-1Researchers in the Department of Chemical and Biological Engineering at Princeton University have developed a new method for synthesizing nanoparticles or microparticles comprised of aggregated nanoparticles having a hydrophilic core and a less polar shell. Biologically derived therapeutics, or biologics, are the most rapidly...
Published: 8/2/2023   |   Inventor(s): Robert Pagels, Robert Prud'homme, Chester Markwalter
Keywords(s): Chemistry, drug delivery, Imaging
Category(s): Biotechnology/Pharmaceuticals, Medical Devices/Diagnostics

Enhanced Adjunctive Therapies for Microbial Infections and Imaging

Princeton Docket # 16-3183-1Researchers in the Department of Chemical and Biological Engineering at Princeton University have developed a nanocarrier based approach to enable and enhance adjunctive therapies for microbial infections by simultaneous encapsulation and delivery of all components.Microbial infections have become increasingly difficult to...
Published: 2/14/2024   |   Inventor(s): Robert Prud'homme, Hoang Lu
Keywords(s): antibiotics, drug delivery, Imaging, nanotechnology
Category(s): Biotechnology/Pharmaceuticals

Polymer Janus Nanoparticles by Flash NanoPrecipitation

Polymer Janus Nanoparticles By Flash NanoPrecipitation Princeton Docket # 14-2981 Janus particles are characterized by two physically distinct regions within or on the surface of the particle. Polymer Janus nanoparticles, in particular, contain at least two different polymer regions. At present, only a few ingenious routes for the generation of...
Published: 9/6/2022   |   Inventor(s): Rodney Priestley, Robert Prud'homme, Chris Sosa
Keywords(s): biomarker/diagnostic, Biotechnology/Pharmaceuticals, catalyst, Chemistry, drug delivery, Imaging
Category(s): Biotechnology/Pharmaceuticals, Medical Devices/Diagnostics, Chemistry

Formation of Nano-Emulsions by Bursting Bubbles in a Liquid-Liquid Interface

A Novel and Low-Cost Method for Nano-emulsion Preparation Princeton Docket # 13-2871-1 Nano-emulsions are used in novel multiphase materials for home and personal care products, drug-delivery applications, structured liquids, etc. However, current methods for the preparation of nano-emulsions require either high-energy methods or sophisticated devices....
Published: 3/30/2022   |   Inventor(s): Luben Arnaudov, Simeon Stoyanov, Howard Stone, Jie Feng, Matthieu Roché, Daniele Vigolo
Keywords(s): Chemistry, drug delivery, materials
Category(s): Chemistry, Biotechnology/Pharmaceuticals, Materials

A Novel, Concentrated, High loading Nanoparticle-based Formulation of Progesterone for Emergency Traumatic Brain Injury, Princeton Docket # 12-2766

A Novel, Concentrated, High loading Nanoparticle-based Formulation of Progesterone for Emergency Traumatic Brain Injury Princeton Docket # 12-2766-1 Unmet Need Progesterone is a water-insoluble steroidal hormone that is a promising therapeutic for treating traumatic brain injury (TBI). However, it is difficult to formulate the steroid for emergency...
Published: 3/30/2022   |   Inventor(s): Robert Prud'homme, Carlos Figueroa
Keywords(s): drug delivery
Category(s): Biotechnology/Pharmaceuticals

Incorporation of Cisplatin, Carboplatin and Oxalplatin in to a Trinuclear Iron-Platinum Intervalent Charge Transfer Complex: Options for the photochemical Delivery of Cisplatin to Targeted Sites

Princeton University Invention # 08-2484 Cisplatin is a leading chemotherapy agent; however its effectiveness is limited by its severe side effects. Researchers at Princeton University and the University of Medicine and Dentistry New Jersey, Department of Chemistry and Department of Pathology and Laboratory Medicine, respectively have synthesized...
Published: 3/30/2022   |   Inventor(s): Andrew Bocarsly, Patricia Fitzgerald-Bocarsly, Amanda Tricarico, Kate Keets
Keywords(s): cancer/oncology, drug delivery
Category(s): Biotechnology/Pharmaceuticals