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Search Results - protein+engineering
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ClpP is a Major Regulator in NO Stressed E Coli
Discovery of ClpP Protein, a Major Regulator in Nitric Oxide Stressed Escherichia coli, for Anti-infective Development Strategies Princeton Docket # 15-3064 Antibiotic resistance has become a public health crisis, while the rate of new antibiotic development declines. A promising solution is antivirulence therapy, which targets host-pathogen interactions,...
Published: 2/14/2024
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Inventor(s):
Mark Brynildsen
,
Jonathan Robinson
Keywords(s):
antibiotics
,
anti-infectives
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biomarker/diagnostic
,
life science research tools
,
metabolic engineering
,
protein engineering
Category(s):
Biotechnology/Pharmaceuticals
,
Chemistry
Phosphohistidine Mimetics for the Development of Anti-Phosphohistidine Antibodies and Identification of Therapeutic Targets
Phosphohistidine Mimetics for the Development of Anti-Phosphohistidine Antibodies and Identification of Therapeutic Targets Princeton Docket # 14-2972 Researchers in the Department of Chemistry at Princeton University have developed the first phosphohistidine (pHis)-specific antibody, which has enabled the selective detection and identification of...
Published: 4/15/2025
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Inventor(s):
Tom Muir
,
Rob Oslund
,
Jung-Min Kee
Keywords(s):
antibody
,
biomarker/diagnostic
,
Biotechnology/Pharmaceuticals
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Chemistry
,
drug discovery
,
drug target
,
life science research tools
,
posttranslational modification
,
protein engineering
,
protein phosphorylation
,
therapeutic
Category(s):
Biotechnology/Pharmaceuticals
,
Chemistry